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  • اریترپویتین

    سلام.لطفا اگر اطلاعاتی که راجع به هورمون اریتروپویتین دارید به خصوص تستهای آزمایشگاهی برای اندازه گیری EPO برای من بفرستید.هم چنین اسم کیتهایی که برای EPO استفاده میشود.ممنون

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  • erythropoietin

    What is erythropoietin? Erythropoietin (EPO) is a hormone produced by the kidney that promotes the formation of red blood cells by the bone marrow. The kidney cells that make erythropoietin are specialized so that they are sensitive to low oxygen levels in the blood that travels through the kidney. These cells make and release erythropoietin when the oxygen level is too low. The low oxygen level may indicate anemia, a diminished number of red blood cells, or hemoglobin molecules that carry oxygen through the body. Chemically, what is erythropoietin (EPO)? Erythropoietin is a protein with an attached sugar (a glycoprotein). It is one of a number of similar glycoproteins that serve as stimulants for the growth of specific types of blood cells in the bone marrow. What exactly does erythropoietin (EPO) do? Erythropoietin stimulates the bone marrow to produce more red blood cells. The resultant rise in red cells increases the oxygen-carrying capacity of the blood. As the prime regulator of red cell production, erythropoietin's major functions are to: Promote the development of red blood cells. Initiate the synthesis of hemoglobin, the molecule within red blood cells that transports oxygen. Is the kidney the sole source of erythropoietin? No. Erythropoietin is produced to a lesser extent by the liver. Only about 10% of the erythropoietin is produced in the liver. The erythropoietin gene has been found on human chromosome 7 (in band 7q21). Different DNA sequences flanking the erythropoietin gene act to control liver versus kidney production of erythropoietin.

    ۱۳۹۱ جمعه ۱۹ آبان | 2 | kavian

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  • epo

    Erythropoietin is not a routine test. It is ordered primarily to help differentiate between different types of anemia and to determine whether the amount of erythropoietin being produced is appropriate for the level of anemia present. It is usually ordered following abnormal findings on a complete blood count (CBC), a group of tests that includes a RBC count and evaluation, a hemoglobin, and a hematocrit. These tests establish the presence and severity of anemia and give the doctor clues as to the likely origin of the anemia. Erythropoietin is ordered to help determine if an insufficiency of the hormone may be causing and/or exacerbating the anemia. In people with chronic kidney disease, the test may be ordered at intervals to evaluate the kidneys' continued ability to produce sufficient erythropoietin. The erythropoietin test is not usually used as a monitoring tool for anemia. This is done by following the RBC count, hemoglobin, hematocrit, and reticulocyte count, a measurement of immature RBCs in the blood and an indicator of bone marrow function. Occasionally, an erythropoietin test may be ordered to help determine if a condition that is causing an excess production of RBCs (polycythemia) is due to an overproduction of erythropoietin.

    ۱۳۹۱ سه شنبه ۹ آبان | 1 | marand

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